Mohamed Lamine Debaghine, holding a doctorate of medicine from Algiers University, opened a medical practice in the eastern Constantine region in 1944.

During the Second World War, he was arrested by colonial authorities for nationalist agitation and for inciting Algerian conscripts to refuse military service in the French army (while also condemning Nazism).

[4] In 1951, his parliamentary mandate ended, and three years later, an armed rebellion for Algeria's independence erupted led by the Front de libération nationale (FLN), a PPA/MTLD splinter group.

[5] Lamine Debaghine was elected minister of foreign affairs in the first lineup of the FLN's government-in-exile, GPRA, under Ferhat Abbas's presidency, holding the post for the period 1958-1960.

A Time Magazine article from 1957 described him as Abbas's close collaborator, "Dr. Mohammed Lamine-Debaghine, 40, [the] bitterly anti-French veteran nationalist who is subject to bouts of depression caused by attacks of neuralgia that partially paralyze his face.