Mohamed Salih Omer (محمد صالح عمر in Arabic) (1934–1969) was a Sudanese politician.
His father was Sheikh Omer Mohamed Al Amein and his mother was Farhein Seid Ahmed Haj.
He graduated from the Faculty of Law (Sharia) of the University of Khartoum on April 1, 1959 (second class upper).
He received his master's degree of Law from the School of Oriental and African Studies, University of London on 24 October 1961.
He was selected as a Minister of Animal Resources in the Ministry of Sirr Al-Khatim Al-Khalifa after the October Revolution in 1964, representing the Islamic Charter Front.