After the assassination of Commander Seyyed Hossein by Golbuddin Hekmatyar, Commander Daud joined Ahmad Shah Massoud and was appointed first as his bodyguard and then as his special assistant After the withdrawal of the Soviet Union and the fall of the Democratic Republic of Afghanistan, and in internal conflicts, a new movement called the Taliban emerged in Kandahar and advanced to take the government of Burhanuddin Rabbani and the fall of Afghanistan.

During his mission, drugs were controlled in many parts of Afghanistan,His campaign against opium poppy cultivation was successful in several provinces, including Logar, Ghazni, Wardak, Paktia, Helmand, Urozgan Paktika and Badakhshan.

He was more in the battlefield and fighting terrorism than sitting in the office, because of this, the insecurity in the north was reduced by 80%, Hamid Karzai, whose first deputy was Marshal Fahim, accused him of genocide against the Pashtuns (from ethnic groups).

[7] In Kunduz during the November 2001 siege were the so-called "Afghan Arabs", foreign volunteers believed to be led by Osama bin Laden.

According to General Mohammed Daud a pro-Taliban leader named "Omar al-Khatab" was leading a force of 1,000 foreign fighters belonging to Osama bin Laden's al-Qaida network.

[7] During the siege the mayor of Kunduz travelled through the surrounding mountains to meet General Mohammed Daud of the Northern Alliance, supposedly in a garden near Taloqan.

"[7] On 27 November 2001 street-to-street fighting began at 7 am in Kunduz, when Northern Alliance troops led by General Mohammed Daud advanced into town.

[11] General Mohammed Daud was named Deputy Ministry of Interior for Counternarcotics by Afghan President Hamid Karzai in October 2004.

Daud and his staff worked with U.S. and British officials in implementing the Afghan government's expanded counternarcotics enforcement plan.

Soon following his appointment, Daud led an Afghan delegation that participated in a thirty night session of the sub-commission on illicit Drug Traffic and related matters in the Near and Middle East (HONLEA) in Beirut, Lebanon.

General Mohammad Daud delivered a presentation on the counter narcotics activities of the government of Afghanistan, achievements and problems still being faced.

[1] President Hamid Karzai took steps to establish landlocked Afghanistan as a trade hub connecting the Middle East, Central Asia and Europe.

Kabul has been particularly interested in swiftly opening trading routes in Central Asia, where there is a vast market for Afghan goods.

[16] One of the girls who was attacked was quoted as saying, "We were going to school on foot when two unknown people on a motorcycle came close to us and threw acid in our faces", 16-year-old Atifa told the BBC.

The attack on the girls, who had been wearing all-covering burqas, drew wide condemnation including from President Hamid Karzai and U.S. First Lady Laura Bush.

"[20] Daud told reporters that the ten Afghans arrested had been promised 100,000 Pakistani rupees (US$1,300) each by Taliban in Pakistan.

Daud said his ministry had opened a bank account to collect money for the girls' medical treatment and education.

"[21] Opium from Afghanistan provides more than 90 per cent of the world's total supply, funding international drug syndicates with billions of US dollars in profits every year.

"[23] The head of the UN's drugs agency said in 2010 that the Taliban had made $US100 million the previous year by levying a 10% tax on opium-growing farmers.

[25] In December 2008 Daud spoke at a U.N. conference in Kabul, Afghanistan,[26] and said that Afghan law enforcement agencies needed international assistance in training and equipment.

Daud informed the participants that the "poppy eradication force" would complete its training soon and would be deployed to the southern provinces of Afghanistan.

The General suggested posting liaison officers to Pakistan, Iran and Tajikistan in order to foster international cooperation.

The switch in strategy has an obvious logic: it provides opium money for the Taliban to sustain itself and helps it to win over the farming communities.

[29] In a continued effort to curb the opium trade in Afghanistan Mohammed Duad reported in June 2008 that police in Kabul set fire to 7.5 tonnes of narcotics.

In April 2009, the Afghan anti-drug officers burned more than six-and-a-half tons of seized heroin, opium, hashish and drug-manufacturing chemicals worth up to £70 million on the UK market.

A Kandahar resident who has had close contact with the drugs trade said that laboratories, often just comprising metal drums and a large press, are mainly located in the border areas.

[31] Daud was assassinated in a Taliban bomb attack in Taloqan,[32][33] after a meeting held in the headquarters of the provincial governor of Takhar Province.

[5][34] Daud was accused of being involved in the narcotics trade and using his post as head of the counter-narcotics police to provide safe passage to smugglers.