Mohammed Ali Ndume (born 20 November 1959) is a Nigerian politician who has served as the senator representing Borno South senatorial district since 2011.

His exceptional superlative brilliance saw him emerging in constant First position in class at Comprehensive Secondary School Mubi.

He proceeded to Federal Polytechnic Ilaro in Ogun State between 1982 – 1983 for his compulsory National Youth Service Corps (NYSC).

On graduation, he returned to Nigeria and continued with his teaching career with the Ramat Polytechnic Maiduguri, Borno State until 2003, when he fully involved in politics.

Alhaji Sanda Garba, who had been the only aspirant for the South Borno Senate seat, stepped down to make way for Ndume as the PDP candidate.

[9][10][11] Ndume was removed from his position due to his closeness to the Presidency and support for Economic and Financial Crimes Commission (EFCC) Chairman nominee, Ibrahim Magu.

[9] Political alignments and re-alignments saw him forming CPC with 20 of his colleagues which eventually coalesced into APC, the present ruling party.

He was re-elected in the 2015 Senatorial elections and became the Leader of the Senate of the Federal Republic of Nigeria in the 8th Assembly until 2017 when he was replaced with Ahmad Ibrahim Lawan.

Ndume has constituency projects spread across all nine local government areas in his senatorial district (Borno South).

Ndume has drilled twenty boreholes and donated some numbers of tractors in each of the 9 local government area of Borno South.