Mokola lyssavirus

The majority of isolates have come from domestic cats exhibiting symptoms characteristically associated to rabies virus infection.

[2][3] The rabies vaccine does not confer cross-protective immunity to Mokola virus, and no other known treatment for MOKV exists.

The second patient ultimately suffered from paralysis and a terminal coma as a result of the MOKV infection.

[1] The MOKV genome consists of a non-segmented, single-stranded, negative-sense RNA molecule of 11,939 nucleotides in length.

There is one significant difference between the symptoms observed in domestic cats infected with MOKV and those with rabies virus.

MOKV-infected domestic cats do not demonstrate the unprovoked aggressive behaviour typically associated with rabies virus-infected mammals.

Mokola virus was first isolated from Crocidura shrews collected in the Mokola forest, Ibadan, Oyo State, Nigeria