[1][4] It covers an area of about 4,577 square kilometers of fairly undisturbed Guinea savannah in the northern part of Ghana.

A long-term study has been done on Mole National Park to understand the impact of human hunters on the animals in the preserve.

This has allowed for some long-term studies, in particular, of relatively undisturbed sites compared to similar areas of densely populated equatorial West Africa.

[11] The program was co-founded by Ashanti Chief Nana Kwasi Agyemang, who hopes to re-ignite local interest in the honey and eventually export it to other countries in Africa.

pallidiciliatum, and two endemic members of the Asclepiadaceae subfamily, the vine Gongronema obscurum, and the edible geophyte, Raphionacme vignei.

[6][17] Among the 344 listed bird species are the martial eagle, the white-headed and palm-nut vultures, saddle-billed storks, herons, egrets, the Abyssinian roller, the violet turaco, various shrikes and the red-throated bee-eater.

[20] Mole National Park, like other Ghanaian game preserves, is poorly funded for prevention of poaching.

[23] Other tourist attractions around the Mole area include Bui National Park, Paga Crocodile Pond, Larabanga Mosque, Cathedral Basilica of Our Lady of the Seven Sorrows among others.