[2] In November 1949, with the seminal paper, "Sickle Cell Anemia, a Molecular Disease",[3] in Science magazine, Linus Pauling, Harvey Itano and their collaborators laid the groundwork for establishing the field of molecular medicine.
[7] Another paper in Science by Pauling in 1968,[8] introduced and defined this view of molecular medicine that focuses on natural and nutritional substances used for treatment and prevention.
Published research and progress was slow until the 1970s' "biological revolution" that introduced many new techniques and commercial applications.
[11] Combining contemporary medical studies with the field of biochemistry, it offers a bridge between the two subjects.
In some universities molecular medicine is combined with another discipline such as chemistry, functioning as an additional study to enrich the undergraduate program.