[2] Monalisa graduated from the Pontifícia Universidade Católica de São Paulo.

During her studies, she worked as a clerk in a rental car company to pay for her college tuition.

Between 4 January and 16 March 2010, Monalisa was the temporary presenter of Bom Dia São Paulo, as its main anchor, Mariana Godoy, was on vacation.

In 2014, she hosted the parades of samba schools of São Paulo[3] and at the end of this year, Monalisa become the first presenter of the new TV news live program Hora Um da Notícia on Rede Globo, which is aired at 5:00am brasilia time ever since.

[4] On 3 August 2019, Perrone left Rede Globo to accept "an irrefusable offer" made by CNN Brazil.