Monte Isola (also known by the name of the main island Montisola; Brescian: Muntìsola) is a town and comune in the province of Brescia, in Lombardy.

The bordering municipalities are Iseo, Marone, Sale Marasino, Sulzano, Parzanica, Tavernola Bergamasca and Sarnico.

There are two main ports Carzano and Peschieria with a frequent ferry service with the surrounding mainland villages, including Iseo.

The first written document mentioning "Insulae curtis" dates from 905, when the island was listed among the properties of the monastery of S. Salvatore in Brescia.

In June and early July, 2016, Monte Isola was the site of The Floating Piers by artists Christo and Jeanne-Claude.

The shrine of Madonna della Ceriola stands 600 metres (1,969 feet) above sea level, the highest spot on the island.