He was signed by the San Francisco 49ers as an undrafted free agent in 2011.
On July 29, 2011, the San Francisco 49ers signed Simmons as an undrafted free agent.
On the next day, he cleared waivers and was signed to the 49ers' practice squad.
Simmons was signed by the Philadelphia Eagles on March 5, 2012.
On October 23, 2012, Simmons was signed by the Indianapolis Colts and placed on the practice squad.