Morehouse is a city in New Madrid County, Missouri, United States.

[4] Morehouse lies along Missouri Route 114 west of Sikeston.

According to the United States Census Bureau, the city has a total area of 0.79 square miles (2.05 km2), all land.

There were 499 housing units at an average density of 631.6 per square mile (243.9/km2).

31.5% of all households were made up of individuals, and 14.6% had someone living alone who was 65 years of age or older.

There were 492 housing units at an average density of 601.5 per square mile (232.2/km2).

25.9% of all households were made up of individuals, and 15.0% had someone living alone who was 65 years of age or older.