In 2002, The Billboard Guide to Contemporary Christian Music described the album's sound as "punk-meets-metal grind-core".

[1] A bundle containing Mortification and Scrolls of the Megilloth was released on KMG Records in 1998 and on Rowe Productions in 2015, with the latter being exclusively on cassette.

Although not as popular as its 1992 follow-up album Scrolls of the Megilloth, Mortification became reputive in both Christian and secular metal scenes for its remarkably brutal output.

[2] Andrew Tompkins, from the Australian Christian metal band Paramaecium, and Derek Sean and Roger Martinez, from the American Christian metal band Vengeance Rising, were additional musicians on the album, with Sean contributing additional lead guitar and both Martinez and Tompkins contributing additional backing vocals; Martinez was also the producer and one of the two mixers on the album, the other being Gil Morales.

The songs "The Destroyer Beholds" and "The Majestic Infiltration of Order" were originally titled "Infectious Growth" and "God Rulz".