The trees can be found in Ngogo in Kibale National Park in Uganda, where they are a food source for chimpanzees.

[2] Afromorus mesozygia is a dioecuous tree that can grow up to 35 m tall, the bark is smooth, greyish in color with irregular white patches.

[3][4] Surface of leaflets has a leathery or papery look, the leaflets are elliptical to broadly ovate in shape and tend to be between 3-13 cm long and 2-8 cm wide with a margin that is serrate to crenate.

Leaves and stem bark extracts are used in decoctions for pain management.

Wood obtained from the species is used for carpentry work and also gathered for use as firewood.