Moshe Spitzer was born on 8 July 1900 in the town of Boskovice, in Moravia, Austro-Hungarian Empire (today the Czech Republic) to a traditional Jewish family.
After his studies, he worked between 1927-1928 as a research assistant at the Prussian Academy of Sciences (Akademie der Wissenschaften) in Berlin.
During World War II, many of the 1,000 fragments of the manuscript were lost, and the text survives only in Spitzer's transcript.
As part of this position, he maintained extensive correspondence with many writers and poets, including Shmuel Yosef Agnon, Else Lasker-Schuler, Uri Zvi Greenberg, and others.
[1] Spitzer was married to Pepa Hammerman, born in Drohobych in 1903, and father of three: Daniel Yosef, Amitai and Esther Yehudit.