Mostafa Khan Mesbahzadeh (Persian: مصطفی مصباح‌زاده; August 18, 1908 – December 25, 2006) was an Iranian Publisher, President of Kayhan Media Corporation, Founder of the Iranian College of Press and Communication ("Daneshkadeh-ye Matbou'at va Oloum-e Ejtema'i", Persian: دانشکده مطبوعات و علوم اجتماعی), University Professor, Member of Parliament and Senator, Member of the Senate of Iran.

[1] Dr. Mostafa Mesbahzadeh turned Kayhan into the largest media group in the Middle East, with daily and weekly publications, magazines dedicated to youth, to sports (Kayhan-e Varzeshi), to children (Kayhan-e Bachcheha), to women (Zan-e Rouz), and international edition in English (Kayhan International).

He was one of the students sent to Europe by the Iranian government during the reign of Reza Shah Pahlavi.

[2][3] In 1942, Dr. Mesbahzadeh founded Kayhan with the help of Mohammad Reza Shah Pahlavi.

After a long period of illness, Mostafa Mesbahzadeh died on 25 November 2006 in San Diego.