Mothers and Sons is a 2006 collection of short stories written by Irish writer Colm Tóibín and published in 2006.

The book was published in hardback by Picador, and each of its stories explores an aspect of the mother-son relationship.

The stories are as follows: "The Use of Reason" "A Song" "The Name of the Game" "Famous Blue Raincoat" "A Priest in the Family" "A Journey" "Three Friends" "A Summer Job" "A Long Winter" Some of the stories in Mothers and Sons, like other Tóibín fiction, explore homosexuality in Ireland.

In addition to mother-son relationships, Tóibín considers gayness alongside Catholicism, and how the two can be compatible in an Irish context.

Tóibín has spoken about the economic disparity between short story collections and novels, the former being unlikely to fetch as much popular interest, or, therefore, money, which is the reason (or so he says) he writes in the first place.