Motlatsi Keseabetwe Segokgo was born in Tlokweng, Bechuanaland Protectorate, in 1928.
He then moved from education to politics, joining the Bechuanaland Democratic Party.
[1] He was elected to the National Assembly of Botswana in 1965 to represent the Kgatleng and Tlokweng constituency.
[2] Segokgo was appointed Minister of Finance upon taking office in the 1st Parliament of Botswana.
He was accused of corruption while in office, and President Seretse Khama asked Segokgo to resign from the cabinet.