The station has two platforms and is on the Mid Cheshire Line, with hourly train services to Manchester Piccadilly and Chester.

[1] At the same time passenger services on the Helsby line, via Manley, ceased and Manley station was closed to passengers, however the line remained open for freight until 1991 and Mouldsworth Junction was managed by a signal box at the end of the platform.

As part of this rationalisation work, the Mouldsworth to Mickle Trafford section was also reduced to a single line.

The West Cheshire Railway line from Helsby closed to passengers as long ago as May 1875 (following the opening of the Chester line), but once carried significant volumes of oil and petrochemical traffic from the refineries near Stanlow and Thornton towards Crewe and points south via Middlewich.

A few months later, a major fire seriously damaged the signal box at Helsby West Cheshire Junction and this led to the immediate closure of the line on 14 September 1991.

The old formation is still just visible at the western end of the station, but it is now heavily overgrown and inaccessible.

On Sundays, a two-hourly service to Chester and Manchester was introduced, with the latter continuing to Southport, via Wigan Wallgate and Bolton.

[13] As part of Northern's proposed December 2022 timetable (which focuses on additional services within the Manchester area), an additional 4 trains per day between Chester and Stockport (2 in each direction) have been proposed during peak hours on Mondays to Saturdays.