In 2006, he was called into the South African Sevens rugby team, making some domestic appearances for Western Province and the Boland Cavaliers.
He represented the national sevens team until 2009, when he announced he wanted to return to the fifteen-a-side game.
Mpho also made history during the 2009 British & Irish Lions tour to South Africa, when he became the first player to score a try for the newly created Southern Kings rugby franchise.
He played in seven of their nine games that season and scored three tries, making him the joint top try scorer for the EP Kings in that competition.
He made 20 appearances and scored 10 tries,[7] to finish in the top ten of the try-scoring charts of the competition.