[8][1]: 2 Wards (2016 population)[9]: 174 In 2022 the Tanzania National Bureau of Statistics report there were 215,438 people in the district, from 103,165 in 2012.

[1]: 4,24 There are 29 primary schools in the districts teaching 20,308 students, of whom 10,049 are girls and 10,259 are boys.

The district has 1 College (Mizengo Pinda Campus College-SUA), which provide Bachelor in Bee Resources Management, Diploma in Crop production and Certificate in Tourism and Hunting, college capacity holding more than 300 students [1]: 9-14 The district has high food insecurity and illnesses.

[14]: 703 [1]: 19,26-27 Some of the wild animals of the Mpimbwe District are elephants, lions, hippopotamus, hyena, buffalos, giraffes, and pigs.

The Katavi National Park and Rukwa Game Reserve are located in, and adjacent, to the district.

[1]: 23 [15] There still exist conflicts with wildlife, but it is decreasing with very little livestock loss to lions or hyena today.