The film follows the titular character as he tries to find a life he can be happy in by traveling through time with the help of a fairy named Sicura and the companionship of his boss's dog, Gastone.
After removing Gastone's ability to bark- to his and Mr. Rossi's despair- she drops the two off in the middle ages in an unspecified area of Europe, which she states is her period of origin.
The prince, angry at having been tricked by a witch into kissing a dog, the two, along with Mr. Rossi, down as the three escape to a time in Egypt during the reign of Tutankhamun.
The witch walks off to find more people to poison, Mr. Rossi is enslaved by Tutankhamun to finish building a pyramid, and Gastone is taken in by the Egyptians as a God.
Gastone sees this and, thinking Mr. Rossi is actually trying to time travel again, blows the whistle to send the pair to the early colonial American West.
They first must escape a shootout in which they have been set up to be killed, and then from a fatal fall down a waterfall made by massive rainstorm- a storm triggered by Gastone's harmonica performance for an unnamed Indigenous American tribe.
[4][5] The German dub of the film received a DVD release as a part of a box set spanning the Mr. Rossi franchise.