Barrister Muhammad Ali Khan Saif (Pashto: محمد علی خان سیف) is a Pakistani politician from Swabi, Khyber Pakhtunkhwa,[2] He had been a member of Senate of Pakistan, from March 2015 to March 2021.

He is currently serving as advisor to Chief Minister Khyber Pakhtunkhwa, Ali Amin Gandapur on Information and Public Relations in the PTI government since March 2024.

[6] He was a member of the Musharraf-led All Pakistan Muslim League (APML) before joining the Muttahida Qaumi Movement (MQM) in 2013.

He then joined Pakistan Tehreek-e-Insaf (PTI) in March 2021, one day before his term as a senator ended after meeting with Imran Khan and Fawad Chaudhry.

In this role, he broadcast many statements such as supporting Gandapur, Imran Khan,[11] PTI, denouncing PML-N,[12] and commenting on judicial matters related to PTI as a barrister,[13] as well as announcing Gandapur’s Khyber Pakhtunkhwa life insurance scheme.