He appears to have performed the role of a sort of troubleshooter, often being sent on special missions requiring status and finesse, such as dealing with difficult local rulers and frontier regions.
[4][3] At one point, he was instructed to lead an army into Transoxiana, the domain of his brother Ulugh Beg, when the latter was discovered to be planning an expedition which their father had not approved.
[6][7] Gawhar Shad kept Muhammad Juki excluded from positions of power, refusing him any influence in the divan, something which was bestowed on Ala al-Dawla as well as his other nephew Abdal-Latif.
[4] When Shah Rukh fell dangerously ill in 1444, Muhammad Juki, by then also governor of Balkh, immediately moved to the capital Herat in order to gain an advantage in the expected succession struggle.
[8] Muhammad Juki, suffering from a lingering illness which may have been exasperated by Gawhar Shad's hostility, died in Sarakhs in 1445, predeceasing his father.