Muhammad Sakizli (Arabic: محمد الساقزلي) (1892–14 January 1976[1]) was the Prime Minister of Cyrenaica from 18 March 1950 to 24 December 1951.

After a short-lived government under Omar Pasha El Kikhia, Muhammad Sakizli formed a new cabinet in March 1950.

[3] After King Idris I of Libya declared its independence 24 December 1951, Sakizli's title changed to be "Governor" of Cyrenaica and remained in that post until May 1952.

Consequently, protests erupted in Tripoli, organized by Tripolitania's governor As-Siddig al-Mutassir, against the court's decision which cancelled the King Idris's order.

[6] On 7 April, the cabinet was summoned, while the Tripoli protests were going on, and governor al-Mutassir was continuing to run the legislative elections, which means actually the defying of the court's decision.