[1][2] Ssegirinya was born in Butale, Kadugala, Masaka District, Uganda on 17 January 1987,[3] to a family of Catholics as the first of five children.

[10] He later won election to become the area MP after defeating nine other contestants including then incumbent Abdulatif Ssebagala Ssengendo and former Deputy Lord Mayor Sulaiman Kidandala.

He contested the 2016 Forum for Democratic Change party primaries for Kawempe north parliamentary seat, but he lost.

[10] In 2021, Ssegirinya successfully contested the Kawempe north constituency on the National Unity Platform (NUP) party ticket.

[13][14][15][16][17] On 3 September 2021, Ssegirinya was summoned by Uganda police force to appear before the Criminal Investigation Department for questioning over his alleged involvement in rebel activities in Greater Masaka region.

On 10 August 2023, Ssegirinya arrived in Netherlands to receive specialized treatment from AMC Amsterdam for his torture wounds.