Muhammad Sultan

He was the ruler who arranged Jesuit Bento de Goes' Caravan, sent by the third Mughal emperor Akbar in 1603, to the border of the Ming dynasty.

Gois came to Yarkand in November 1603, was received by Muhammad Khan and spent in the country almost one and a half year, visiting Khotan, Aksu, Kucha, Chalish and Turpan.

Gois mentioned that Muhammad Khan was governing the country through his direct relatives like Hen sitting on eggs in the nest , he also indicated that Chalish (Kingdom of Cialis) had very strong fortress, here he had open dispute with local ruler about the God and religion.

Khoja Ishaq Wali, 4th son of Nakshbandi teacher Mahdum-i-Azam (Great Master), journeyed to Tarim Basin with his disciples upon invitation of Abdul Karim Khan, and after several years he established Sufi Order Nakshbandi Khojagan Ishaqiyya in the Kashgar region, followers of this Sufi Order later became known as Kara Taghliks.

Before his death in 1599 Ishaq even named Muhammad Sultan the Naqshbandi Grand Master-Ishaq's spiritual successor-thus assuring the Ishaqiyya's continued status in the region.