Sardar Muhammad Yaqoob Khan (Urdu: سردار محمد یعقوب خان) is an Azad Kashmiri businessman and politician.

He belongs to a prominent Sudhan family and is the brother of Late Haji Muhammad Zaman Khan, former MLA and a well-known figure in Azad Kashmir's political and social circles.

Muhammad Yaqoob Khan has had a distinguished political career, serving as a Member of the Azad Jammu & Kashmir Legislative Assembly on four occasions.

During his tenure, he held various ministerial positions, including Minister for Health, Population Welfare & Hydro Electric Board, and Housing & Planning.

Khan founded Brother Construction Y-K (Pvt) Ltd., which has developed two successful housing societies: Al Madina City: Adjacent to Sectors C-18 and C-19 of Islamabad.