[3][4] Before the October Revolution, Mansurov was one of the richest people of Bukhara, a member and patron of the Jadidist movement.

In 1920–1921, trade and industry inspector (minister) of the Bukhara People's Soviet Republic.

Muhyiddin Mansurov was the chairman of the Bukhara Economic Council from March 1921 to April 1923.

Mansurov had four sons and one daughter: Isom, Abdulkadir, Amin, Khairullo Muhiddinovlar and Matlabkhan Muhiddinova.

His sons Isom, Abdulkadir, Amin were members of the "Young Bukhara" movement, besides, Isom managed his father's business and the "Mansurov Trading House", Abduqadir later became the chairman of the USSR, and Amin worked as an authorized representative of the USSR in the RSFSR.