Mulberry High School (also referred to as Mulberry Senior High School) is a four-year public high school located in Mulberry, Florida, serving the city and surrounding areas.

In 1914, a second high school was constructed; it was a two-story brick building with six classrooms and an auditorium, costing approximately $12,500.

[3] In 1921, the first edition of the MHS yearbook was published, titled The Mulberry Tree in honor of the city's famed mulberry tree.

During the Great Depression, many schools cut their terms or lost their accreditation, and the state of Florida ran out of money, but MHS was able to stay open and retain accreditation thanks to taxes paid by area phosphate firms.

[5] In summer of 2020 ground was broken on the baseball field to begin construction on a brand new 3-floor high school done in the architectural style known as International.