The ground was inaugurated in 2001 as a replacement for the Ibn-e-Qasim Bagh Stadium located at that time in the center of Multan.

The first Test match at the stadium took place in August 2001 between Pakistan and Bangladesh, while the first One Day International was held on 9 September 2003 between the same teams.

[5] This stadium hosted its first Pakistan Super League match on 26 February 2020 between Multan Sultans and Peshawar Zalmi.

On 30 May 2022, the PCB announced that Multan Cricket Stadium would host a three match ODI series against the West Indies in June.

[6] In August 2022, the PCB announced that Multan would serve as one of the venues for the home Test series against England in December 2022.