It has hosted many concerts and events, perhaps being best known as the site of many of the New Orleans Mardi Gras krewe balls.

On August 24, 1956, Joe Brown defeated Wallace “Bud” Smith to win the lightweight title in a fifteen-round split decision.

On October 29, 1988, the Road Warriors defeated the Midnight Express (professional wrestling) to win the NWA World Tag Team titles at the auditorium.

Jeff Auditorium in honor of the creator of many of local recreational programs for Black children during the Jim Crow era.

[4] The venue was a temporary casino before the new Harrah's New Orleans building on Canal Street was opened in 1999.