Located in north-western Uganda, it spreads inland from the shores of Lake Albert around the Victoria Nile up to the Karuma Falls.

[2] The driving distance from Masindi, the nearest large town, to the Kibanda area of the national park is about 72 km (45 mi).

[8] Between 1907 and 1912, the inhabitants of an area of about 13,000 km2 (5,000 sq mi) were evacuated due to sleeping sickness spread by tsetse flies.

[11] Murchison Falls National Park and the adjacent Bugondo Forest Reserve host 76 mammal species such as chimpanzees as well as Uganda's largest Nile crocodile population.

There are 450 known bird species including the shoe-billed stork, dwarf kingfisher, Goliath heron, white-thighed hornbill and great blue turaco.