[7][4] This forest is a home to many species which include chimpanzees,[8][3][9][10] forest amphibians (Golden Puddle Frog and Kivu Clawed Frog), bats (Duke of Abruzzi's, silver and mongalia free tailed bats), plant species (Mutuba trees) and birds (Yellow-fronted tinkerbird).

[11][4] In 2008, the National Forestry Authority (NFA) staff planted trees in the Wambabya forest on 2,000 ha (4,900 acres) of land that were encroached upon by human activity.

[5] Some of the human activities in the area that are affecting the forest cover include charcoal burning, logging, poaching, deforestation and agriculture such as rice and tobacco farming.

The project targeted 3,000 households in the districts of Kikuube and Hoima and the beneficiaries received tree seedlings, improved seeds of beans, banana suckers, maize, beehives and goats.

[16] The construction of the 1,443 km (897 mi) East African Crude Oil Pipeline (EACOP) faced resistance by climate activists and environmentalists that is supposed to originate from the Kabaale Industrial Park in Hoima passing through Wambabya, Bugoma and Taala Central Forest Reserves and other places in Uganda to port Tanga in Tanzania.