Murdock is a village in Cass County, Nebraska, United States.

Murdock was established circa 1890 when the Chicago, Rock Island and Pacific Railroad was extended to that point.

[5] According to the United States Census Bureau, the village has a total area of 0.13 square miles (0.34 km2), all land.

The racial makeup of the village was 98.51% White, 0.37% Native American, 0.37% Asian, and 0.74% from two or more races.

28.2% of all households were made up of individuals, and 18.2% had someone living alone who was 65 years of age or older.

About 2.3% of families and 2.5% of the population were below the poverty line, including 3.8% of those under the age of eighteen and none of those 65 or over.