Brandt was a keen gardener, with her fellow artist, James Nolan recalling her "passionate concern for the arts and the environment.

[2][3] She was commissioned to produce murals for a number of religious buildings including the St Anthony's shrine in the Franciscan church of Adam and Eve in Dublin (1938–40).

[2] Brandt was commissioned to design a postage stamp in 1949 to mark the international recognition of the new Irish Republic.

[5] She was commissioned to paint the portraits of many Dublin notables, among them Sir Alfred Chester Beatty[4] and George O'Brien.

One of her most famous works is the group portrait which hangs in the foyer of the Gate Theatre, Dublin which features Christine Longford, Hilton Edwards, and Micheál Mac Liammóir.

Brandt also produced drawings for periodicals including Dublin Opinion and Ireland of the Welcomes, as well as illustrating Terence de Vere White's Leinster (1968).