The sheath-tailed mouse (Mus fragilicauda) is a mouse found in two locations in central Thailand and in Laos.

It is the only known Mus species to lose its tail integument when handled.

It is sometimes found with the fawn-colored mouse.

In Nakhon Ratchasima Province, Thailand, Mus fragilicauda has been recorded in Ban Nong Sanga and Tumbon.

It has also been recorded in Loei, Thailand and in Lamam, Sekong Province, Laos.