Muscadine is an unincorporated community in Cleburne County, Alabama, United States.

Muscadine is 2.75 miles (4.43 km) east of Fruithurst.

Muscadine has a post office with ZIP code 36269, a general store, and a bar.

[2][3] Muscadine was an incorporated community for a time and was listed on the U.S. Census from 1890 to 1930.

This Cleburne County, Alabama state location article is a stub.