The Muscocho Lake is a body of water crossed by the Obatogamau River in the territory of Eeyou Istchee James Bay (municipality), in the administrative area of Nord-du-Québec, in the province of Quebec, in Canada.

The surface of Muscocho Lake is usually frozen from early November to mid-May, however safe ice movement is generally from mid-November to mid-April.

Lake Muscocho has an angled shape (open to the southwest) due to a peninsula advancing north-east on 5.0 kilometres (3.1 mi).

This mouth is located at: The main hydrographic slopes near Lake Muscocho are: The oldest mention of this hydronym on maps dates back to 1927.

[2] The toponym "Lake Muscocho" was formalized on December 5, 1968, by the Commission de toponymie du Québec, when it was created.