Muse is an unincorporated community in Le Flore County, Oklahoma, United States.

Muse is located along Oklahoma State Highway 63, 17 miles (27 km) southeast of Talihina.

A post office was established at Muse, Indian Territory on October 1, 1896.

On May 11, 1927, another post office called Muse, Oklahoma was established at a slightly different location.

[3] At the time of its founding, Muse was located in Wade County, a part of the Apukshunnubbee District of the Choctaw Nation.