Mutant (1984) was the second role-playing game published by Target Games, and the rules were based on the Basic Role-Playing system, and its post-apocalyptic Scandinavian setting was populated by mutant humans and animals.

After a space probe returns to Earth from Mars with surface samples, which turn out to contain an incurable disease that causes an epidemic, human civilization collapses.

Some of the released experiments managed to survive to become the ancestors of the game's mutant population.

The only survivors from the old world are the few humans that were put into cryogenic sleep, cyborgs and androids.

Mutant 2 also introduced more high tech into the world like the class Cryogenic frozen human.