Mutant Storm Empire is a multi-directional shoot 'em up by PomPom Games and the sequel to Mutant Storm Reloaded released for the Xbox 360's Xbox Live Arcade service.

Mutant Storm Empire improves on the original Xbox 360 incarnation by creating a seamless world that lets the user travel from room to room without having to enter a loading screen.

Higher points can be reached by playing on more difficult settings and attaining combo bonuses by stringing together kills of the same enemy colour, which is made difficult as one needs to allow other enemy types to populate the screen to achieve this.

The game features a two-player cooperative mode that is playable locally and on Xbox Live.

Mutant Storm Empire received mixed to positive reviews from critics upon release.