Muthuramalinga Sethupathi II (1841–1873) was the zamindar of Ramnad estate from 1862 to 1873.
He was adopted by his aunt Parvatha Vardhani Ammal Nachiyar, the Rani of Ramnad.
He was a patron of arts and music.
Muthuramalinga Sethupathi married Muthathal Nachiyar.
The couple had a son, Bhaskara Sethupathi.