It was serialized online on the user-generated novel publishing website Shōsetsuka ni Narō from December 2019 to June 2023.

High school student Asahi Ikusaba, an RPG otaku who has always dreamed of adventuring in another world, gets his wish when he is rendered comatose after getting hit by a car while saving a child.

Written by Konoe, My One-Hit Kill Sister was serialized online as a web novel on the user-generated novel publishing site Shōsetsuka ni Narō from December 28, 2019, to June 17, 2023.

[8][9] Shogakukan collected its chapters in twelve tankōbon volumes, released from July 10, 2020,[10] to September 12, 2023.

[23][3] TrySail performed the opening theme song "Karei One Turn" (華麗ワンターン, "Splendid One Turn"),[24] while VALIS performed the ending theme song "Mukyū Platonic" (無窮プラトニック, "Forever Platonic").