Reluctantly but dutifully, Theodosia capitulates to her father's wishes and marries Joseph Alston in February 1801.

The story moves on through Aaron Burr's time as Vice President: his controversial actions dueling Alexander Hamilton; his working to take over Mexico, naming himself as king; and his subsequent trial.

Kirkus Reviews noted, "The author, while making the most of her material, has managed to sustain an objective viewpoint towards her characters (at some sacrifice of the sympathy she might have claimed)".

[1] Though reviewers frequently comment on the meticulous research Seton put into her books, Richard N. Cote claims there are historical inaccuracies with My Theodosia.

Both the putative romance with Meriwether Lewis and the depiction of the Alston marriage as unhappy are examples of fiction, not fact.