[1] This sponge is found in the Caribbean Sea and the Gulf of Mexico and usually grows in association with a small group of coral genera.

[2][3] Mycale laevis usually grows on the undersurface of certain species of corals that form flat plates.

Often the sponge is found covering the under side of an entire groups of colonial corals.

In the absence of suitable coral species, Mycale laevis is able to live directly on rocks and under boulders as an encrusting or massive sponge[4] and also on calcareous worm tubes.

[3] Mycale laevis is found on reefs in the Caribbean Sea, the Gulf of Mexico, the West Indies, the Bahamas and Florida at depths between 1 and 80 metres (3.3 and 262.5 ft) but is more common at depths greater than 25 metres (82 ft).