[3] It is endemic to the Pacaraima Mountains in Guyana and known from the region of its type locality in the Kaieteur National Park and from Imbaimadai.

The tympanum is distinct and relatively large, only slightly obscured by the well-developed supratympanic fold.

The call is audible over long distances and is often preceded by a groan or several isolated notes.

[2] Myersiohyla liliae occurs in primary forest and its edge with savanna, near large bromeliads.

It is threatened by gold and diamond mining, also occurring within the Kaieteur National Park.