In the past, Mykola Kniazhytskyi held key positions in media companies and Tonis, STB, and UT-1 TV channels, was head of Hazeta 24.

In the late 1990s, Mykola Kniazhytskyi obtained second degree at the Faculty of International Law and Business of the Institute of Postgraduate education of Lviv University.

[3] From February to June 1992, Kniazhytskyi was a special correspondent for political analysis and forecast of the State TV and Radio Broadcaster of Ukraine, and a co-host of Oleksandr Tkachenko in "Vikna" (the Windows) program.

[4] From December 1994 to October 1998, Kniazhytskyi was President of "International Media Center — STB" CJSC, hosted program "Reitynh" (the Rating).

After a number of journalists, including Vitaly Portnikov, resigned and accused the owners of attempts to impose censorship (Oleksandr Kosterin was identified as a person likely to be the main beneficiary), Mykola Kniazhytskyi also left the company in November 2007.

[7] In 2008, Mykola Kniazhytskyi with the part of employees who left "MediaDim" launched a new project, TBi TV channel ("International Media Company").

Two weeks later Kniazhytskyi reported that officers of the tax police "began to terrorize" people who provided services to the TV channel.

[9] The press service of then-President Viktor Yanukovych released a statement that the President expressed his concern and ordered to check the legality of the case.

[14] Kniazhytskyi stated that his sudden dismissal from the post of a member of the National Council of Television and Radio Broadcasting of Ukraine was related to his balloting to the Verkhovna Rada.

In 2016, Mykola Kniazhytskyi was elected Head of EU-Ukraine Parliamentary Association Committee and Co-Head of group for interparliamentary relations with the Republic of Poland.

The draft law introduces mechanisms of state support of national cinematography, and enhances measures of fight against Internet piracy.

4303 "On Amendments to Some Laws of Ukraine Regarding the Limitation of Use of Media Production of the Aggressor State" aimed to protection of national interests and fight against Russian propaganda.

On April 9, 2015, he voted in favor of recognizing the status of fighters for the independence of Ukraine in the 20th century of all nationalist formations, including those participating in the occupation of modern Ukrainian lands on the side of the German Empire and the Third Reich.

5313 "On Amendments to Some Laws of Ukraine on the Language of Audiovisual (Electronic) Media", proposing mandatory quotas for TV programs and films in Ukrainian.

In the 2019 Ukrainian parliamentary election he was re-elected to the Verkhovna Rada, this time from Ukraine's 116th electoral district in Lviv Oblast as a candidate of European Solidarity.

Kniazhytskyi is married to Larysa Frantsivna Kniazhytska (née Chekhovska, born 1970), a fellow university student who is currently a press manager.