Myles Joseph Ambrose (July 21, 1926 – June 3, 2014) was an American lawyer and United States federal government official.

He served as the Commissioner of Customs under President Richard M. Nixon and paved the way for the establishment of the Drug Enforcement Administration.

[1] He joined the United States Department of the Treasury in 1957, when he was appointed as chief coordinator of law enforcement and he prosecuted gang members.

[1][2] From 1960 to 1963, he served as the executive director of the Waterfront Commission of New York Harbor,[1] where he prosecuted organized crime figures.

[2] Under his leadership, he oversaw the implementation of Operation Intercept, which consisted in searching vehicles entering the United States from Mexico.

[2] The program was discontinued within weeks; instead, the Mexican police was expected to search for illicit drugs in cars driving into U.S.