12, see text Myrmekiaphila is a genus of North American mygalomorph trapdoor spiders in the family Euctenizidae, and was first described by G. F. Atkinson in 1886.

The palpal tibia of the males are modified in a way that distinguishes them from other mygalomorph spiders of North America.

Some species construct side chambers that can be closed off by secondary trap doors, a unique feature among Cyrtaucheniidae.

[6] As of May 2019[update] it contains twelve species restricted to the southeastern United States, but found in a wide variety of habitats.

These range from northern Virginia along the Appalachian Mountains southward through West Virginia, Kentucky, North and South Carolina, Tennessee and northern Georgia into the southeastern plain of Alabama, Mississippi Florida, and the temperate deciduous forest of central Texas with dry climates and relatively high altitudes.