She was a radio fixture from 1932 to 1946 thanks to the popular soap opera Myrt and Marge, playing the elder half of the title as well as having created and written the show.

[1] Vail thought of the show while living in the Chicago area, after having spent several years as a vaudeville performer (often with her husband, George Damerel), basing it largely on her own experiences.

This forced her to turn the show's writing over to a colleague named Charles Thomas, who wrote a storyline in which Myrt was kidnapped by gangsters, allowing Vail to recuperate completely.

She made one last effort with the original concept in 1946, creating a transcribed version of Myrt and Marge that used refurbished scripts.

[citation needed] A longtime resident of Haworth, New Jersey, Vail died in Kansas City, Missouri in 1978, aged 90.